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Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion.

Journal Title:
Proceedings of the National Academy of Sciences of the United States of America.
Journal Volume/Issue:
Mar 15, 1994. v. 91 (6)
Main Author:
Efrat, S.
Other Authors:
Leiser, M., Wu, Y.J., Fusco-Demane, D., Emran, O.A., Surana, M., Jetton, T.L., Magnuson, M.A., Wier, G., and Fleischer, N.
Format:
Article
Language:
English
Subjects:
mice
islets of Langerhans
glucokinase
gene expression
antisense RNA
insulin secretion
glucose
animal models
diabetes
View in NAL's Catalog:
IND20404914